Our Scientific Background
We have revealed that uterine defects predates pregnancy-related diseases bringing new opportunities for early detection and prevention strategies
MATERNAL CONTRIBUTION TO PREECLAMPSIA
It’s characterized by hypertension, proteinuria and organ damage and long-term consequences such as cardiovascular diseases
A full understanding of the pathogenesis of PE remains elusive and new treatments are needed.
Early prediction is essential for reducing health impact in mothers and their babies
Our research provides evidence of a maternal contribution to preeclampsia based on defective decidualization during and years after pregnancy
Our technology improves pregnancy health by taking a novel utero-centric concept of preeclampsia
01
Decidualization prepares the uterus for embryo invasion and placentation
We demonstrated a maternal contribution to severe preeclampsia through defective decidualization
02
The placenta provides nutrients and oxygen to the embryo
Defective decidualization impacts maternal and fetal communication during abnormal placentation
03
C-RNA molecules reflect dynamic changes in pregnancy health
Our technology based on C-RNA sequencing enables to predict pregnancy complications before symptoms appear
Our investigation decidualization opens up new horizons for identifying circulating RNAs that can predict complications early during pregnancy