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Our Scientific Background

We have revealed that uterine defects predates pregnancy-related diseases bringing new opportunities for early detection and prevention strategies

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Clinical study

MATERNAL CONTRIBUTION TO PREECLAMPSIA

Preeclampsia accounts for thousands of maternal and infant deaths worldwide
It’s characterized by hypertension, proteinuria and organ damage and long-term consequences such as cardiovascular diseases
A full understanding of the pathogenesis of PE remains elusive and new treatments are needed.

Early prediction is essential for reducing health impact in mothers and their babies

Our research provides evidence of a maternal contribution to preeclampsia based on defective decidualization during and years after pregnancy

Pregnant woman

Our technology improves pregnancy health by taking a novel utero-centric concept of preeclampsia

01

Decidualization prepares the uterus for embryo invasion and placentation​
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We demonstrated a maternal contribution to severe preeclampsia through defective decidualization

02

The placenta provides nutrients and oxygen to the embryo
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Defective decidualization impacts maternal and fetal communication during abnormal placentation​

03

C-RNA molecules reflect dynamic changes in pregnancy health
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Our technology based on C-RNA sequencing enables to predict pregnancy complications before symptoms appear​

Our investigation decidualization opens up new horizons for identifying circulating RNAs that can predict complications early during pregnancy

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Our Main Publications

Main publications infographic

Our Main Publications

Main publications infographic

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